Antibiotic and AntimicrobialAgents Thiocolchicoside 98%CAS:602-41-5

CAS No.:602-41-5

Other Names:THIOCOLCHICOSIDE

MF:C27H33NO10S

EINECS No.:210-017-7

Type:Antibiotic andAntimicrobial Agents

Grade Standard:Feed Grade,Medicine Grade

Usage:Animal Pharmaceuticals

Purity:98%

Shelf life:2 Years

MW:563.62

Appearance:Yellow Powder

storage temp.:Refrigerator

Description >>

Thiocolchicoside is extractedfrom the seeds of Gloriosa Superba.
Gloriosa is a genus of five or six species in the plant family Colchicaceae,from tropical Africa and Asia. They are tender, tuberous rooted deciduousperennials, adapted to summer rainfall with a dormant dry season. Their nativerange is Africa, Southeastern Asia and parts of Malaysia, but they are nowwidely cultivated.
Gloriosa superba is the national flower of Zimbabwe, former Rhodesia (where itis a protected plant). It is also the state flower of Tamilnadu state in India.

Function

Thiocolchicoside is a musclerelaxant with anti-inflammatory and analgesic effects. It acts as a competitiveGABAA receptor antagonist and also inhibits glycine receptors with similarpotency and nicotinic acetylcholine receptors to a much lesser extent. It haspowerful convulsant activity and should not be used in seizure-prone individuals.
Main functions are as follows:
1. Anti-cancer
2. Anti-gout
3. Cure - hepatitis and cirrhosis of liver

Application >>

Thiocolchicoside (Muscoril,Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesiceffects. It acts as a competitive GABAA receptor antagonist and also glycinereceptor antagonist with similar potency and nicotinic acetylcholine receptorsto a much lesser extent. It has powerful convulsant activity and should not beused in seizure-prone individuals. This mechanism of action would be expectedto induce withdrawal symptoms in gabaminergic (ex. barbiturates, carbamates,ethanol) dependent individuals, including the potentially lethal deleriumtremens.