Basicinformation
Chlorhexidine99% disinfect and antiseptic medicine; bactericide, strong function ofbroad-spectrum bacteriostasis, sterilization; take effective for killgram-positive bacteria gram-negative bacteria; used for disinfecting hands,skin, washing wound.
Chlorhexidinesalts are widely used in pharmaceutical formulations in Europe and Japan fortheir antimicrobial properties.Although mainly used as disinfectants,chlorhexidine salts are also used as antimicrobial preservatives.
As excipients, chlorhexidine salts are mainly used for thepreservation of eye-drops at a concentration of 0.01% w/v; generally theacetate or gluconate salt is used for thispurpose.
Solutions containing 0.002–0.006% w/v chlorhexidine gluconatehave also been used for the disinfection of hydrophilic contact lenses.
For skin disinfection, chlorhexidine has been formulated as a0.5% w/v solution in 70% v/v ethanol and, in conjunction with detergents, as a4% w/v surgical scrub. Chlorhexidine salts may also be used in topicalantiseptic creams, mouthwashes, dental
gels, and in urology for catheter sterilization and bladderirrigation.Chlorhexidine salts have additionally been used asconstituents ofmedicated dressings, dusting powders, sprays, and creams.
Function
1) In cosmetics andpersonal care products, Chlorhexidine and its salts (Chlorohexidine Dihydrochloride,Chlorhexidine
Digluconate, Chlorhexidine Diacetate) are usedin the formulation of eye makeup, makeup foundations, mouthwashes, hair dyesand bleaches, and other skin care and hair care products;
2) Chlorhexidine has been used in medicalpractice and these ingredients, particularly the Digluconate salt, haveextensive use in
dentistry because they inhibit plaqueformation;
3) Chlorhexidine is used as a topicalantiseptic skin scrub in hospital and household settings;
4) For use in animals, it is used as a topicaldisinfectant of wounds.