Probenecid
CAS57-66-9
Probenecid is a medication that increases uricacid excretion in the urine. It is primarily used in treating gout andhyperuricemia.
Probenecid was developed as an alternative tocaronamide to competitively inhibit renal excretion of some drugs, therebyincreasing their plasma concentration and prolonging their effects.
Certification of Analysis
Items | Specifications |
Appearance | Free-flowing beadlets |
Colour | yellowish |
Dispersibility | Cold water spread |
Fineness (US standard Sieves) |
|
-through sieve No.30 | 100% smaller than 30 |
-through sieve No.40 | Min.90% smaller than 30 |
-through sieve No.100 | Max.15% smaller than 30 |
Loss on drying % | ≤8 |
Untapped Density: (g/mL) | 0.50-0.70 |
Tapped Density: (g/mL) | 0.70-0.75 |
Sulfated Ash (%) | <1 |
PH (1% solution) | 6.6-7.0 |
Pb (ppm) | ≤10.0 |
Arsenic (ppm) | ≤1.0 |
Vitamin D3 (IU/g) | ≥100.000 |
Total bacterial count(cfu/g) | ≤1×103 |
Coli form bacteria (MPN/100g) | ≤40 |
Fungi and yeast (cfu/g) | ≤50 |
Salmonella: (/25g) | Negative |
Function&Application
Bothtretionirum and Vitamin A can stimulate skin growth and keep epidermic normal.Howerver, to spread on part of skin has no actual effect. Taking orally vitaminA is benefit to treat skin disorders. Applying vitamin A acid to skin partlycould produce intensive pharmacological action. External use can slow down skinaging process for solarization, remove tiny wrinkles, and reduce skinroughness, so skin will become ruddy.
Side-effectand Notice:
Don`t spread it in thin skin. Proper lowerconcentration (no more than 0.025%)can avoid such reaction as scalp off,Scorching fever and erythema, which is caused by drastic dilation of bloodvessel. Please insist on using the product and you will get preferable curativeeffect when you find such normal reaction as erythema, scorch fever andhypodynia. Discontinue it and apply some oleiferous skin-care products to theskin site, if the reaction is severe. Cold cream concentration less than 0.025,show some effect upon treating acne and skin roughness kept cool and closed.
